CFI-400945
orally available, selective inhibitor of polo-like kinase 4 (PLK4)
Product Specifications
CAS Number
1338806-73-7
Product Name Alternative
(1S,2R)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one
Field of Research
Cell Cycle Checkpoint PLK
Purity
0.9837
Form
A crystalline solid
Solubility
insoluble in H2O; ≥109.8 mg/mL in DMSO; ≥93 mg/mL in EtOH
Smiles
C[C@@H]1O[C@H](C)CN(CC2=CC=C(/C=C/C3=NNC4=C3C=CC([C@H]5[C@@]6(C(C=C(OC)C=C7)=C7NC6=O)C5)=C4)C=C2)C1
Molecular Formula
C33H34N4O3
Molecular Weight
534.7
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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