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AD57 (hydrochloride)

polypharmacological cancer therapeutic that inhibits RET.

Product Specifications

Product Name Alternative

N-[4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea, monohydrochloride

Field of Research

Apoptosis c-RET

Purity

0.98

Form

A crystalline solid

Solubility

≤5mg/ml in ethanol;10mg/ml in DMSO;14mg/ml in dimethyl formamide

Smiles

CC(C)N1C2=NC=NC(N)=C2C(C3=CC=C(NC(NC4=CC(C(F)(F)F)=CC=C4)=O)C=C3)=N1.Cl

Molecular Formula

C22H20F3N7O·HCl

Molecular Weight

491.9

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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