Covidcil-19
Product Specifications
UNSPSC Description
Covidcil-19 (compound C5) avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with a Kd of 11 nM. Covidcil-19 stabilizes the hairpin’s folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/covidcil-19.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(NC2=NC(NC)=C3C=CC=CC3=N2)=CC=C1)O
Molecular Weight
294.31
References & Citations
[1]Hafeez S Haniff, et al. Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders. ACS Cent Sci. 2020 Oct 28;6(10):1713-1721.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W728005/Covidcil-19-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W728005/
Clinical Information
No Development Reported
CAS Number
1225177-95-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6179853-01 0.1 mL
CSF2 (Colony Stimulating Factor 2 (Granulocyte-Macrophage), GMCSF, MGC131935, MGC138897) (HRP)
Ask
View Details MBS6179853-02 5x 0.1 mL
CSF2 (Colony Stimulating Factor 2 (Granulocyte-Macrophage), GMCSF, MGC131935, MGC138897) (HRP)
Ask
View Details 
ARP46217_P050-HRP 100 µL
SEPT6 Antibody - N-terminal region: HRP (ARP46217_P050-HRP)
Ask
View Details