Netarsudil (AR-13324)

1253952-02-1

(R)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate dihydrochloride

TGF-β Smad Signaling ROCK

0.9982

A solid

≥26.3 mg/mL in H2O with gentle warming and ultrasonic; insoluble in EtOH; ≥7.783 mg/mL in DMSO

[H]Cl.[H]Cl.O=C(OCC1=CC=C([C@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C

C28H29Cl2N3O3

526.45

Blue ice

Store at -20°C.