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Nepetoidin B

Product Specifications

UNSPSC Description

Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research[1][2].

Target Antigen

Bacterial; Fungal; NF-κB

Type

Natural Products

Related Pathways

Anti-infection;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nepetoidin-b.html

Solubility

10 mM in DMSO

Smiles

O=C(O/C=C\C1=CC=C(O)C(O)=C1)/C=C/C2=CC=C(O)C(O)=C2

Molecular Weight

314.29

References & Citations

[1]Kim M, et al. Nepetoidin B from Salvia plebeia R. Br. Inhibits Inflammation by Modulating the NF-κB and Nrf2/HO-1 Signaling Pathways in Macrophage Cells. Antioxidants (Basel). 2021 Jul 28;10(8):1208. |[2]Wu X, et al. Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways. Phytother Res. 2017 Jul;31(7):1072-1077.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N8263/Nepetoidin-B-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N8263/

Clinical Information

No Development Reported

CAS Number

55486-06-1

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