A 331440 (hydrochloride)
A 331440 hydrochloride is a histamine H3 receptor antagonist. A 331440 hydrochloride binds potently and selectively to human and rat histamine H3 receptors (Ki≤25 nM) . A 331440 hydrochloride can be used for antiobesity research[1].
Product Specifications
CAS Number
1049740-32-0
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/a-331440-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.[H]Cl.CN(C)[C@H](CC1)CN1CCCOC2=CC=C(C3=CC=C(C=C3)C#N)C=C2
Molecular Formula
C22H29Cl2N3O
Molecular Weight
422.39
References & Citations
[1]Hancock AA, et al. Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist. Eur J Pharmacol. 2004 Mar 8;487 (1-3) :183-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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