What is the catalog number for DL-AP5?

The catalog number for DL-AP5 is HY-100714.

What sizes are available for DL-AP5?

DL-AP5 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does DL-AP5 come in?

DL-AP5 is available in 6 different pack sizes.

DL-AP5 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DL-AP5?

DL-AP5 is manufactured by QuantiMol.

What is the estimated delivery time for DL-AP5?

Estimated delivery time for DL-AP5 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DL-AP5?

The safety data sheet for DL-AP5 is available here: http://file.medchemexpress.com/batch_PDF/HY-100714/DL-AP5-SDS-MedChemExpress.pdf.

DL-AP5

DL-AP5 (2-APV) is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 shows significantly antinociceptive activity. DL-AP5 specifically blocks on channels in the rabbit retina[1][2][3].

Product Specifications

CAS Number

76326-31-3

Product Name Alternative

2-APV; DL-2-Amino-5-phosphonovaleric acid

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dl-ap5.html

Purity

98.0

Solubility

H2O : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC(CCCP(O)(O)=O)C(O)=O

Molecular Formula

C5H12NO5P

Molecular Weight

197.13

Precautions

H315, H319, H335

References & Citations

[1]Murray CW, et al. Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model. Pain. 1991;44 (2) :179-185.|[2]Massey SC, et al. N-methyl-D-aspartate receptors of ganglion cells in rabbit retina. J Neurophysiol. 1990;63 (1) :16-30.|[3]Jafari-Sabet M. NMDA receptor blockers prevents the facilitatory effects of post-training intra-dorsal hippocampal NMDA and physostigmine on memory retention of passive avoidance learning in rats. Behav Brain Res. 2006 Apr 25;169 (1) :120-7.|[4]Taati M, et al. The effects of DL-AP5 and glutamate on ghrelin-induced feeding behavior in 3-h food-deprived broiler cockerels. J Physiol Biochem. 2011 Jun;67 (2) :217-23.|[5]Chen T, et al. Glutamate-induced rapid induction of Arc/Arg3.1 requires NMDA receptor-mediated phosphorylation of ERK and CREB. Neurosci Lett. 2017 Nov 20;661:23-28.