Kushenol B
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].
Product Specifications
CAS Number
99217-64-8
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kushenol-b.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\C[C@@H](C(C)=C)CC1=C2C(C(C[C@@H](C3=C(C=C(C=C3)O)O)O2)=O)=C(C(C/C=C(C)\C)=C1O)O
Molecular Formula
C30H36O6
Molecular Weight
492.60
References & Citations
[1]Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening. Mol Med Rep
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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