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ON123300

multi-targeted kinase inhibitor,inhibits CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn

Product Specifications

CAS Number

1357470-29-1

Product Name Alternative

8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile

Field of Research

Cell Cycle Checkpoint Cyclin-Dependent Kinases

Purity

0.9951

Form

A solid

Solubility

≥21.5 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O

Smiles

N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O

Molecular Formula

C24H27N7O

Molecular Weight

429.52

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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