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AlF-NOTA-c-d-VAP

AlF-NOTA-c-d-VAP is a peptide positron emission tomography (PET) probe that used for targeted tumor imaging of GRP78. AlF-NOTA-c-d-VAP demonstrates high stability in vitro and in vivo[1].

Product Specifications

UNSPSC

12171500

Target

HSP; Radionuclide-Drug Conjugates (RDCs)

Type

Dye Reagents

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/alf-nota-c-d-vap.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](NC([C@H](NC([C@H](NC([C@@](NC([C@H](NC([C@H](N)CO)=O)CC(N)=O)=O)([H])[C@@H](O)C)=O)CCCNC(N)=N)=O)C(C)C)=O)C(N(CCC1)[C@H]1C(N[C@@H](C(O)=O)CSC(CC2=O)C(N2CCNC(C[N]34CC[N]5(CC[N](CC4)6C7)CC(O[Al]536(F)OC7=O)=O)=O)=O)=O)=O

Molecular Formula

C51H83AlFN17O19S

Molecular Weight

1316.35

References & Citations

[1]Jiawen Huang, et al. Synthesis and Evaluation of [18F]AlF-NOTA-c-DVAP: A Novel PET Probe for Imaging GRP78 in Cancer. Mol Pharm. 2024 Mar 30.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

RDC Bifunctional Chelator

Frequently Asked Questions

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