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LOXO-101

tropomyosin receptor kinases (TRK) inhibitor

Product Specifications

Product Name Alternative

(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate

Sequence

Larotrectinib

Field of Research

Tyrosine Kinase Trk

Purity

0.9951

Form

A solid

Solubility

≥18.47 mg/mL in DMSO; ≥2.14 mg/mL in EtOH; ≥29.65 mg/mL in H2O

Smiles

O=S(O)(O)=O.O=C(N1C[C@@H](O)CC1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2

Molecular Formula

C21H24F2N6O6S

Molecular Weight

526.51

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

1223405-08-0

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