Raseglurant
Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol (HY-14538) -induced catalepsy in mice[1][2].
Product Specifications
CAS Number
[757950-09-7]
Product Name Alternative
ADX-10059
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/raseglurant.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2
Molecular Formula
C15H13FN2
Molecular Weight
240.28
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14866/Raseglurant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14866/Raseglurant-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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