Pexmetinib (ARRY-614)
dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase
Product Specifications
Product Name Alternative
1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea
Field of Research
MAPK Signaling p38
Purity
0.9953
Form
A solid
Solubility
insoluble in H2O; ≥107.6 mg/mL in DMSO; ≥113 mg/mL in EtOH
Smiles
CC1=CC=C(N2C(NC(NCC3=CC(F)=CC=C3OC4=CC=C5C(C=NN5CCO)=C4)=O)=CC(C(C)(C)C)=N2)C=C1
Molecular Formula
C31H33FN6O3
Molecular Weight
556.64
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
945614-12-0
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