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Pexmetinib (ARRY-614)

dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase

Product Specifications

CAS Number

945614-12-0

Product Name Alternative

1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea

Field of Research

MAPK Signaling p38

Purity

0.9953

Form

A solid

Solubility

insoluble in H2O; ≥107.6 mg/mL in DMSO; ≥113 mg/mL in EtOH

Smiles

CC1=CC=C(N2C(NC(NCC3=CC(F)=CC=C3OC4=CC=C5C(C=NN5CCO)=C4)=O)=CC(C(C)(C)C)=N2)C=C1

Molecular Formula

C31H33FN6O3

Molecular Weight

556.64

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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