Rolapitant HCl

552292-08-7 (free base)

(5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]dec-1-en-2-ol hydrochloride

GPCR G protein NK Receptor

0.9913

insoluble in H2O; ≥28.7 mg/mL in EtOH with ultrasonic; ≥32.9 mg/mL in DMSO

C[C@]([H])(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@]2(CC[C@]3(CCC(O)=N3)CN2)C4=CC=CC=C4.Cl

C25H27ClF6N2O2

536.94

Blue ice

Store at -20°C.