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Entrectinib

Orally active inhibitor of ALK kinase

Product Specifications

CAS Number

1108743-60-7

Product Name Alternative

(Z)-N-(5-(3,5-difluorobenzyl)-1H-indazol-3(2H)-ylidene)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide

Field of Research

Tyrosine Kinase ALK

Purity

0.9884

Form

A solid

Solubility

≥28.05 mg/mL in DMSO; insoluble in H2O; ≥9.82 mg/mL in EtOH with ultrasonic

Smiles

CN1CCN(C2=CC(NC3CCOCC3)=C(C(/N=C4C5=C(NN/4)C=CC(CC6=CC(F)=CC(F)=C6)=C5)=O)C=C2)CC1

Molecular Formula

C31H34F2N6O2

Molecular Weight

560.64

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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