GDC-0994

1453848-26-4

(S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one

MAPK Signaling MEK1 2

0.9885

A solid

≥44.1 mg/mL in DMSO; insoluble in H2O; ≥19.2 mg/mL in EtOH

CN1C(NC2=NC=CC(C(C=CN3[C@](C4=CC(F)=C(Cl)C=C4)([H])CO)=CC3=O)=N2)=CC=N1

C21H18ClFN6O2

440.86

Blue ice

Store at -20°C.