AK-068-OH
AK-068-OH (Compound 49) is an active control of ligand for target protein for PROTAC.
Product Specifications
CAS Number
2982851-61-4
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; PROTAC; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ak-068-oh.html
Smiles
FC(C1=CC=C2C(C=C(C(N[C@@H](C(C)(C)C)C(N3[C@H](C(N4C[C@@H](C5=CC=CC=C5)OCC4)=O)C[C@H](O)C3)=O)=O)S2)=C1)(P(O)(O)=O)F
Molecular Formula
C31H36F2N3O8PS
Molecular Weight
679.67
References & Citations
[1]Kaneshige A, et, al. Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader. J Med Chem. 2024 Sep 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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