AK-068-OH

2982851-61-4

12352005

Ligands for Target Protein for PROTAC; STAT

Reference compound

JAK/STAT Signaling; PROTAC; Stem Cell/Wnt

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/ak-068-oh.html

FC(C1=CC=C2C(C=C(C(N[C@@H](C(C)(C)C)C(N3[C@H](C(N4C[C@@H](C5=CC=CC=C5)OCC4)=O)C[C@H](O)C3)=O)=O)S2)=C1)(P(O)(O)=O)F

C31H36F2N3O8PS

679.67

[1]Kaneshige A, et, al. Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader. J Med Chem. 2024 Sep 23.

Room temperature

Reference compound1

No Development Reported