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Sulindac (Standard)

Sulindac (Standard) is the analytical standard of Sulindac. This product is intended for research and analytical applications. Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac also is an immunomodulatory agent. Sulindac can be used for the research of arthritis of the spine, gouty arthritis and kinds of cancer including colorectal cancer (CRC) and lung cancer[1][2].

Product Specifications

CAS Number

38194-50-2

Product Name Alternative

MK-231 (Standard)

UNSPSC

12352005

Target

NF-κB; PD-1/PD-L1; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; NF-κB; Others

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/sulindac-standard.html

Smiles

O=C(CC(C1=C2C=CC(F)=C1)=C(/C2=C/C3=CC=C(C=C3)S(C)=O)C)O

Molecular Formula

C20H17FO3S

Molecular Weight

356.41

References & Citations

[1]Byong-Ki Cha, et al. Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1. Oncotarget. 2016 Aug 30;7 (35) :57213-57227. |[2]Bin Yi, et al. Sulindac Modulates the Response of Proficient MMR Colorectal Cancer to Anti-PD-L1 Immunotherapy. Mol Cancer Ther. 2021 Jul;20 (7) :1295-1304.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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