CK-3197
CK-3197 is a weak inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl) . CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure[1].
Product Specifications
CAS Number
132523-92-3
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ck-3197.html
Smiles
O=C(C1=C(CC)NC(N1C(C2=CC=CC=C2)=O)=O)C3=CC=C(N4C(C)=NCC4)C=C3
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
References & Citations
[1]Greenberg S, et al. Hemodynamic and myocardial energetic effects of CK-3197, a selective positive inotropic agent. J Cardiovasc Pharmacol. 1991 Jan;17 (1) :145-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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