L-691121
L-691121 exhibits antiarrhythmic efficacy through block of potassium channel and a followed prolonged cardiac potential. L-691121 exhibits embryotoxicity with fetal mortality at the dose of 0.8 mg/kg/day (p.o.) . L-691121 is orally active[1].
Product Specifications
CAS Number
136075-60-0
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-691121.html
Smiles
CS(=O)(NC1=CC=C2C(C(CC3(CCN(CCC4=CC5=NON=C5C=C4)CC3)O2)=O)=C1)=O.[H]Cl
Molecular Formula
C22H25ClN4O5S
Molecular Weight
492.98
References & Citations
[1]Ban Y, et al., Embryotoxic effects of L-691,121, a class III antiarrhythmic agent, in rats. Arch Toxicol. 1994;69 (1) :65-71.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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