β-Caryophyllene-13C, d2

β-Caryophyllene-13C, d2 is 13C and deuterated labeled β-Caryophyllene (HY-N1415) . β-Caryophyllene is a CB2 receptor agonist[1].

Product Specifications

Product Name Alternative

(-) - (E) -Caryophyllene-13C, d2; (−) -β-caryophyllene-13C, d2; (−) -trans-Caryophyllene-13C, d2

UNSPSC

12352211

Target

Cannabinoid Receptor; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

CC1([C@@]2([H])[C@](/C(CC/C=C(CC2)/C)=[13C]([2H])\[2H])([H])C1)C

Molecular Formula

C14 13CH22D2

Molecular Weight

207.36

References & Citations

[1]Cheng Y, et al. β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway. Pharmacology. 2014;94 (1-2) :1-12.|[2]Dahham SS, et al. The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllenefrom the Essential Oil of Aquilaria crassna. Molecules. 2015 Jun 26;20 (7) :11808-29.|[3]de Oliveira CC, et al. Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. Epilepsy Behav. 2016 Mar;56:26-31.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.