Nilofabicin
Nilofabicin is an enoyl- (acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC (90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].
Product Specifications
CAS Number
[934628-27-0]
Product Name Alternative
CG-400549
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nilofabicin.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(OCCC2=CC=CS2)C=CN1CC3=CC=CC(N)=C3C
Molecular Formula
C19H20N2O2S
Molecular Weight
340.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Jong Hwa Yum, et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51 (7) : 2591–2593.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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