AMG 487

473719-41-4

N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide

0.9964

insoluble in H2O; ≥122 mg/mL in EtOH; ≥122.2 mg/mL in DMSO

CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F

C32H28F3N5O4

603.59

Blue ice

Store at -20°C.