GST-FH.4
GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC50 of 24.38 μM[1].
Product Specifications
CAS Number
[1358386-87-4]
UNSPSC
12352005
Target
Glutathione S-transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gst-fh-4.html
Purity
90.0
Smiles
COC1=C(C=CC=C1)N2N=NC(C3=NSC(NC4=CC=C(C(OC)=C4)OC)=N3)=C2C
Molecular Formula
C20H20N6O3S
Molecular Weight
424.49
References & Citations
[1]Brenke JK, et al. Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction. J Biomol Screen. 2016 Jul;21 (6) :596-607.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Curated Selection
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