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GST-FH.4

Product Specifications

UNSPSC Description

GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC50 of 24.38 μM[1].

Target Antigen

Glutathione S-transferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gst-fh-4.html

Purity

90.0

Smiles

COC1=C(C=CC=C1)N2N=NC(C3=NSC(NC4=CC=C(C(OC)=C4)OC)=N3)=C2C

Molecular Weight

424.486

References & Citations

[1]Brenke JK, et al. Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction. J Biomol Screen. 2016 Jul;21(6):596-607.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-160874/GST-FH-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-160874/

Clinical Information

No Development Reported

CAS Number

1358386-87-4

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