GST-FH.4

GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC50 of 24.38 μM[1].

Product Specifications

CAS Number

[1358386-87-4]

UNSPSC

12352005

Target

Glutathione S-transferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gst-fh-4.html

Purity

90.0

Smiles

COC1=C(C=CC=C1)N2N=NC(C3=NSC(NC4=CC=C(C(OC)=C4)OC)=N3)=C2C

Molecular Formula

C20H20N6O3S

Molecular Weight

424.49

References & Citations

[1]Brenke JK, et al. Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction. J Biomol Screen. 2016 Jul;21 (6) :596-607.