6-Hydroxy-TSU-68

6-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517) . It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68[1].

Product Specifications

CAS Number

[1035154-49-4]

UNSPSC

12352005

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-hydroxy-tsu-68.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC(O)=C3)=O)=C1C

Molecular Formula

C18H18N2O4

Molecular Weight

326.35

References & Citations

[1]Ryuichi Kitamura, et al. Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z) -5-[ (1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68) . Drug Metab Dispos. 2008 Jun;36 (6) :1003-9.