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KPT-276

inhibitor of nuclear export (SINE) and CRM1, orally bioavailable

Product Specifications

CAS Number

1421919-75-6

Product Name Alternative

(Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one

Field of Research

Cell Cycle Checkpoint CRM1

Purity

0.9997

Form

A solid

Solubility

insoluble in EtOH; insoluble in H2O; ≥19.85 mg/mL in DMSO

Smiles

C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F

Molecular Formula

C16H10F8N4O

Molecular Weight

426.26

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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