Dabrafenib (GSK2118436)
Inhibitor of BRAF(V600) mutants
Product Specifications
CAS Number
1195765-45-7
Product Name Alternative
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
Field of Research
MAPK Signaling Raf
Purity
0.9836
Form
A solid
Solubility
≥26 mg/mL in DMSO; insoluble in H2O; ≥2.59 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F
Molecular Formula
C23H20F3N5O2S2
Molecular Weight
519.56
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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