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GZD824

Bcr-Abl inhibitor,novel orally bioavailable

Product Specifications

CAS Number

1421783-64-3

Product Name Alternative

3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate

Field of Research

Tyrosine Kinase Bcr-Abl

Purity

0.9846

Form

A solid

Solubility

≥36.25 mg/mL in DMSO; ≥33.95 mg/mL in H2O with ultrasonic; ≥4.71 mg/mL in EtOH with ultrasonic

Smiles

CC1=CC=C(C(NC2=CC=C(CN3CCN(C)CC3)C(C(F)(F)F)=C2)=O)C=C1C#CC4=CN=C5C(C=NN5)=C4.CS(=O)(O)=O.CS(=O)(O)=O

Molecular Formula

C29H27F3N6O·2CH4O3S

Molecular Weight

724.77

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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