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Cabozantinib malate (XL184)

MET andVEGF receptor2 inhibitor

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid

Field of Research

Tyrosine Kinase c-MET

Purity

0.981

Solubility

≥31.8 mg/mL in DMSO; insoluble in H2O; ≥2.5 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C(C(C(=O)O)O)C(=O)O

Molecular Formula

C32H30FN3O10

Molecular Weight

635.59

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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