Refametinib

923032-37-5

N-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]cyclopropane-1-sulfonamide

MAPK Signaling MEK1 2

0.9978

insoluble in H2O; ≥151.8 mg/mL in DMSO; ≥90.2 mg/mL in EtOH

COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F

C19H20F3IN2O5S

572.34

Blue ice

Store at -20°C.