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Bifenazate

Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm[1]. Bifenazate is a positive allosteric modulator of GABA receptor[2]. Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III[3].

Product Specifications

CAS Number

149877-41-8

UNSPSC

12352005

Hazard Statement

H317

Target

GABA Receptor; Insecticide; Mitochondrial Metabolism; Na+/K+ ATPase; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Infection; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bifenazate.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : ≥ 250 mg/mL

Smiles

COC1=CC=C(C2=CC=CC=C2)C=C1NNC(OC(C)C)=O

Molecular Formula

C17H20N2O3

Molecular Weight

300.35

Precautions

H317

References & Citations

[1]Dekeyser, M.A., McDonald, P.T., and Angle, G.W., Jr. The discovery of bifenazate, a novel carbazate acaricide Chimia 57 (11), 702-704 (2003) .|[2]Hiragaki S, et al. A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]. Neurotoxicology. 2012 Jun;33 (3) :307-13.|[3]Ma J, et al., Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environ Pollut. 2021 Apr 1;274:116539.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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