RGLS4326 (sodium)
Product Specifications
UNSPSC Description
RGLS4326 sodium is a first-in-class, short oligonucleotide inhibitor of microRNA-17 (miR-17). RGLS4326 sodium can be used for the research of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 sodium inhibits miR-17 function in HeLa cells with an EC50 value of 28.3 nM[1].
Target Antigen
MicroRNA
Type
Oligonucleotides
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rgls4326-sodium.html
Smiles
[RGLS4326 (sodium)]
Molecular Weight
3289.33
References & Citations
[1]Edmund C Lee, et al. Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease. Nat Commun. 2019 Sep 12;10(1):4148.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139290A/RGLS4326-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139290A/RGLS4326-sodium-SDS-MedChemExpress.pdf
Available Sizes
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