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MK-8745

Aurora A inhibitor,potent and selective

Product Specifications

Product Name Alternative

(3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone

Field of Research

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

Purity

0.9981

Form

A solid

Solubility

≥21.6 mg/mL in DMSO; insoluble in H2O; ≥2.28 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

ClC1=C(F)C(C(N2CCN(CC3=NC(NC4=NC=CS4)=CC=C3)CC2)=O)=CC=C1

Molecular Formula

C20H19ClFN5OS

Molecular Weight

431.91

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

885325-71-3

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