Tankyrase Inhibitors (TNKS) 22

3-((4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-((1r,4r)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)cyclohexyl)propanamide

TNKS 22;TNKS22;TNKS-22

Chromatin Epigenetics PARP DNA Damage DNA Repair PARP Stem Cell Wnt β-catenin

0.98

A solid

insoluble in H2O; insoluble in DMSO; ≥3.07 mg/mL in EtOH with gentle warming

O=C1NC(SCCC(N[C@H]2CC[C@H](C3=NN=C(C4=CC=CC=C4)O3)CC2)=O)=NC5=CC=CC=C51

C25H25N5O3S

475.56

Blue ice

Store at -20°C.