Sotrastaurin (AEB071)

425637-18-9

3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione

AEB 071;AEB-071

TGF-β Smad Signaling PKC

0.9961

A solid

≥21.9 mg/mL in DMSO; insoluble in H2O; ≥2.55 mg/mL in EtOH with ultrasonic

CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65

C25H22N6O2

438.48

Blue ice

Store at -20°C.