ARRY-380

6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine

ARRY380; ARRY 380

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

0.9878

A solid

≥28.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5

C29H27N7O4S

569.63

Blue ice

Store at -20°C.

937265-83-3