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R428

Selective Axl inhibitor

Product Specifications

CAS Number

1037624-75-1

Product Name Alternative

1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine

Sequence

R-428; R 428; BGB324; Bemcentinib

Field of Research

Tyrosine Kinase Axl

Purity

0.9806

Form

A solid

Solubility

≥25 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH

Smiles

C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76

Molecular Formula

C30H34N8

Molecular Weight

506.64

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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