R428
Selective Axl inhibitor
Product Specifications
Product Name Alternative
1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine
Sequence
R-428; R 428; BGB324; Bemcentinib
Field of Research
Tyrosine Kinase Axl
Purity
0.9806
Form
A solid
Solubility
≥25 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
Smiles
C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76
Molecular Formula
C30H34N8
Molecular Weight
506.64
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
1037624-75-1
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