Dacomitinib (PF299804, PF299)
HER inhibitor
Product Specifications
CAS Number
1110813-31-4
Product Name Alternative
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
Sequence
PF-00299804; PF-299804; PF 299804; PF 00299804
Field of Research
JAK STAT Signaling EGFR Tyrosine Kinase EGFR
Purity
0.9987
Form
A solid
Solubility
≥23.5 mg/mL in DMSO; insoluble in H2O; ≥8.76 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4
Molecular Formula
C24H25ClFN5O2
Molecular Weight
469.94
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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