Dacomitinib (PF299804, PF299)

(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide

PF-00299804; PF-299804; PF 299804; PF 00299804

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

0.9987

A solid

≥23.5 mg/mL in DMSO; insoluble in H2O; ≥8.76 mg/mL in EtOH with gentle warming and ultrasonic

COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4

C24H25ClFN5O2

469.94

Blue ice

Store at -20°C.

1110813-31-4