RAF265

927880-90-8

1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine

CHIR-265;RAF 265;RAF-265;CHIR265

MAPK Signaling Raf Tyrosine Kinase VEGFR

0.9924

A solid

≥25.9 mg/mL in DMSO; insoluble in H2O; ≥7.97 mg/mL in EtOH with ultrasonic

CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F

C24H16F6N6O

518.43

Blue ice

Store at -20°C.