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PF-562271

ATP-competitive FAK inhibitor, reversible

Product Specifications

CAS Number

717907-75-0

Product Name Alternative

N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide

Sequence

PF562271;PF 562271

Field of Research

Tyrosine Kinase FAK TGF-β Smad Signaling Pyk2 Tyrosine Kinase Pyk2

Purity

0.9785

Form

A solid

Solubility

≥25.35 mg/mL in DMSO; insoluble in H2O; ≥2.25 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

Molecular Formula

C21H20F3N7O3S

Molecular Weight

507.49

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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