PF-562271
ATP-competitive FAK inhibitor, reversible
Product Specifications
CAS Number
717907-75-0
Product Name Alternative
N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
Sequence
PF562271;PF 562271
Field of Research
Tyrosine Kinase FAK TGF-β Smad Signaling Pyk2 Tyrosine Kinase Pyk2
Purity
0.9785
Form
A solid
Solubility
≥25.35 mg/mL in DMSO; insoluble in H2O; ≥2.25 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
Molecular Formula
C21H20F3N7O3S
Molecular Weight
507.49
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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