Nintedanib (BIBF 1120)
VEGFR/PDGFR/FGFR inhibitor
Product Specifications
Product Name Alternative
methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate
Sequence
Vargatef
Field of Research
Tyrosine Kinase FGFR Tyrosine Kinase PDGFR Tyrosine Kinase VEGFR
Purity
0.9722
Form
A solid
Solubility
insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL in DMSO
Smiles
CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
Molecular Formula
C31H33N5O4
Molecular Weight
539.62
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
656247-17-5
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