TAE684 (NVP-TAE684)

761439-42-3

5-chloro-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine

Tyrosine Kinase ALK

0.99

A solid

≥61.4 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥33.73 mg/mL in EtOH with ultrasonic

CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC

C30H40ClN7O3S

614.2

Blue ice

Store at -20°C.