Afatinib (BIBW2992)
Irreversible EGFR/HER2 inhibitor
Product Specifications
Product Name Alternative
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Field of Research
JAK STAT Signaling EGFR Tyrosine Kinase EGFR Tyrosine Kinase HER2
Purity
0.9883
Form
A solid
Solubility
≥24.3 mg/mL in DMSO; insoluble in H2O; ≥42.1 mg/mL in EtOH with ultrasonic
Smiles
CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Molecular Formula
C24H25ClFN5O3
Molecular Weight
485.94
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
439081-18-2
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