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Regorafenib

Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1

Product Specifications

Product Name Alternative

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

Sequence

BAY 73-4506

Field of Research

Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase PDGFR Tyrosine Kinase VEGFR

Purity

0.9946

Form

A solid

Solubility

≥25.04 mg/mL in DMSO; insoluble in H2O; ≥6.25 mg/mL in EtOH with ultrasonic

Smiles

O=C(NC)C1=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=CC=N1

Molecular Formula

C21H15ClF4N4O3

Molecular Weight

482.82

Shipping Conditions

Blue ice

Storage Conditions

Desiccate at -20°C.

CAS Number

755037-03-7

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