Semagacestat (LY450139)

425386-60-3

(2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide

LY-450139, LY 450139,Semagacestat

Neuroscience Alzheimer Neuroscience Amyloid β Proteases Gamma Secretase Neuroscience Gap Junction

0.994

A solid

insoluble in H2O; ≥18.05 mg/mL in DMSO; ≥40.3 mg/mL in EtOH with ultrasonic

CC(C)C(C(=O)NC(C)C(=O)NC1C2=CC=CC=C2CCN(C1=O)C)O

C19H27N3O4

361.44

Blue ice

Store at -20°C.