Semagacestat (LY450139)
γ-secretase inhibitor
Product Specifications
CAS Number
425386-60-3
Product Name Alternative
(2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide
Sequence
LY-450139, LY 450139,Semagacestat
Field of Research
Neuroscience Alzheimer Neuroscience Amyloid β Proteases Gamma Secretase Neuroscience Gap Junction
Purity
0.994
Form
A solid
Solubility
insoluble in H2O; ≥18.05 mg/mL in DMSO; ≥40.3 mg/mL in EtOH with ultrasonic
Smiles
CC(C)C(C(=O)NC(C)C(=O)NC1C2=CC=CC=C2CCN(C1=O)C)O
Molecular Formula
C19H27N3O4
Molecular Weight
361.44
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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